Orthostatic hypotension (postural hypotension)-Orthostatic hypotension (postural hypotension) - Symptoms & causes - Mayo Clinic (2024)

Overview

Orthostatic hypotension — also called postural hypotension — is a form of low blood pressure that happens when standing after sitting or lying down. Orthostatic hypotension can cause dizziness or lightheadedness and possibly fainting.

Orthostatic hypotension can be mild. Episodes might be brief. However, long-lasting orthostatic hypotension can signal more-serious problems. It's important to see a health care provider if you frequently feel lightheaded when standing up.

Occasional orthostatic hypotension is usually caused by something obvious, such as dehydration or lengthy bed rest. The condition is easily treated. Chronic orthostatic hypotension is usually a sign of another health problem, so treatment depends on the cause.

Symptoms

The most common symptom of orthostatic hypotension is lightheadedness or dizziness when standing after sitting or lying down. Symptoms usually last less than a few minutes.

Orthostatic hypotension signs and symptoms include:

  • Lightheadedness or dizziness upon standing
  • Blurry vision
  • Weakness
  • Fainting (syncope)
  • Confusion

When to see a doctor

Occasional dizziness or lightheadedness can be minor — triggered by mild dehydration, low blood sugar or overheating. Dizziness or lightheadedness can also result from standing after sitting for a long time. If these symptoms happen only occasionally, there's likely no cause for concern.

It's important to see a health care provider for frequent symptoms of orthostatic hypotension. Losing consciousness, even for just a few seconds, is serious. It requires seeing a provider right away.

Keep a record of your symptoms, when they occurred, how long they lasted and what you were doing at the time. Tell your care provider if symptoms occur at times that could be dangerous, such as while driving.

Request an appointment

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Causes

When standing from a sitting or lying position, gravity causes blood to collect in the legs and belly. Blood pressure drops because there's less blood flowing back to the heart.

Usually, special cells (baroreceptors) near the heart and neck arteries sense this lower blood pressure. The baroreceptors send signals to the brain. This tells the heart to beat faster and pump more blood, which evens out blood pressure. These cells also narrow the blood vessels and increase blood pressure.

Orthostatic hypotension occurs when something interrupts the body's process of dealing with the low blood pressure. Many conditions can cause orthostatic hypotension, including:

  • Dehydration. Fever, vomiting, not drinking enough fluids, severe diarrhea and strenuous exercise with a lot of sweating can all lead to dehydration. Dehydration decreases blood volume. Mild dehydration can cause symptoms of orthostatic hypotension, such as weakness, dizziness and fatigue.
  • Heart problems. Some heart conditions that can lead to low blood pressure include extremely low heart rate (bradycardia), heart valve problems, heart attack and heart failure. These conditions prevent the body from quickly pumping more blood when standing up.
  • Endocrine problems. Thyroid conditions, adrenal insufficiency (Addison's disease) and low blood sugar (hypoglycemia) can cause orthostatic hypotension. So can diabetes, which can damage the nerves that help send signals that control blood pressure.
  • Nervous system disorders. Some nervous system disorders, such as Parkinson's disease, multiple system atrophy, Lewy body dementia, pure autonomic failure and amyloidosis, can disrupt the body's ability to control blood pressure.
  • Eating meals. Some people have low blood pressure after eating meals (postprandial hypotension). This condition is more common in older adults.

Risk factors

The risk factors for orthostatic hypotension include:

  • Age. Orthostatic hypotension is common in those who are age 65 and older. Special cells (baroreceptors) near the heart and neck arteries that control blood pressure can slow as you age. It also can be harder for an aging heart to speed up to make up for drops in blood pressure.
  • Medications. These include medications used to treat high blood pressure or heart disease, such as diuretics, alpha blockers, beta blockers, calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors and nitrates.

    Other medications that can increase the risk of orthostatic hypotension include medications used to treat Parkinson's disease, certain antidepressants, certain antipsychotics, muscle relaxants, medications to treat erectile dysfunction and narcotics.

  • Certain diseases. Diseases that can increase the risk of low blood pressure include some heart conditions, such as heart valve problems, heart attack and heart failure. They also include certain nervous system disorders, such as Parkinson's disease. And they include diseases that cause nerve damage (neuropathy), such as diabetes.
  • Heat exposure. Being in a hot environment can cause heavy sweating and possibly dehydration, which can lower blood pressure and trigger orthostatic hypotension.
  • Bed rest. Staying in bed for a long time because of an illness or injury can cause weakness. This can lead to orthostatic hypotension.
  • Alcohol. Drinking alcohol can increase the risk of orthostatic hypotension.

Complications

Persistent orthostatic hypotension can cause serious complications, especially in older adults. These include:

  • Falls. Falling as a result of fainting is a common complication in people with orthostatic hypotension.
  • Stroke. The swings in blood pressure from standing and sitting as a result of orthostatic hypotension can be a risk factor for stroke due to the reduced blood supply to the brain.
  • Cardiovascular diseases. Orthostatic hypotension can be a risk factor for cardiovascular diseases and complications, such as chest pain, heart failure or heart rhythm problems.
Orthostatic hypotension (postural hypotension)-Orthostatic hypotension (postural hypotension) - Symptoms & causes - Mayo Clinic (2024)

FAQs

Orthostatic hypotension (postural hypotension)-Orthostatic hypotension (postural hypotension) - Symptoms & causes - Mayo Clinic? ›

Orthostatic hypotension — also called postural hypotension — is a form of low blood pressure that happens when standing after sitting or lying down. Orthostatic hypotension can cause dizziness or lightheadedness and possibly fainting. Orthostatic hypotension can be mild. Episodes might be brief.

What are three reasons a person could have orthostatic hypotension? ›

Causes of orthostatic hypotension

Fever. Prolonged bed rest. Excessive amounts of alcohol. Some medications, such as some diuretics or antihypertensive (high blood pressure) medications.

What are four drugs causing orthostatic hypotension? ›

Common drugs that cause orthostatic hypo tension are diuretics, alpha-adrenoceptor blockers for prostatic hypertrophy, antihypertensive drugs, and calcium channel blockers. Insulin, levodopa, and tricyclic antidepressants can also cause vasodilation and orthostatic hypotension in predisposed patients.

What is the life expectancy for someone with orthostatic hypotension? ›

Those with orthostatic hypotension survived a mean of 3.19 years after examination 4 (range 0 to 4.75 years), whereas those without orthostatic hypotension survived a mean of 3.37 years (range 0 to 4.83 years).

What are two risks to the person with orthostatic hypotension? ›

[44] Large meta-analyses reported an increased risk of the following with orthostatic hypotension:
  • Falls[1]
  • Heart failure[45]
  • Coronary heart disease[45]
  • Stroke[2]
  • Atrial fibrillation[45]
  • All-cause mortality[2]

What is the ultimate cause of orthostatic hypotension in the elderly? ›

Orthostatic hypotension was negatively associated with weight. We conclude that orthostatic hypotension is common in the elderly and increases with advancing age. It is associated with cardiovascular disease, particularly those manifestations measured objectively, such as carotid stenosis.

What vitamin deficiency causes orthostatic hypotension? ›

Vitamin D3 supplementation is considered a potential intervention to prevent orthostatic hypotension (OH) based on observational evidence that vitamin D levels are inversely associated with OH.

Does drinking water help with orthostatic hypotension? ›

Water drinking elicits a rapid pressor response in patients with autonomic failure and can be used to treat orthostatic and postprandial hypotension. Water drinking moderately reduces orthostatic tachycardia in patients with idiopathic orthostatic intolerance.

What foods help orthostatic hypotension? ›

There are several types of foods that can help raise blood pressure including slowly digested foods like whole grains, beans, protein, and healthy oils. Any healthy foods rich in vitamin B12, folate, caffeine, or salt can help raise blood pressure. DASH Eating Plan. (2021).

What are the two worst blood pressure medications? ›

5 of the worst blood pressure medications
  1. Beta blockers. Usually, beta blockers aren't used as first-choice therapies to lower blood pressure. ...
  2. Loop diuretics. Furosemide (Lasix) is a type of diuretic (water pill) known as a loop diuretic. ...
  3. Alpha blockers. ...
  4. Vasodilators. ...
  5. Alpha-2 agonists.
Feb 14, 2024

Which drug is most likely to cause hypotension? ›

Drugs used for the treatment of psychiatric illnesses are all associated with a significant incidence of orthostatic hypotension: phenothiazines, tricyclic antidepressants and monoamine oxidase inhibitors.

What is the first line treatment for orthostatic hypotension? ›

Fludrocortisone. Fludrocortisone, which is a synthetic mineralocorticoid, is considered first-line therapy for the treatment of orthostatic hypotension.

Who is most at risk for orthostatic hypotension? ›

The risk factors associated with OH include older age; use of antihypertensive drugs; and comorbidities such as hypertension, cardiac failure, and kidney disease. OH is associated with increased risk for cardiovascular mortality in different populations. OH also may lead to falls and syncope.

Should I be worried about orthostatic hypotension? ›

Up to 20% of people over 65 experience some degree of orthostatic hypotension. If it's occasional and the lightheaded feeling lasts less than 15 seconds, just be sure you stay well hydrated. But if it happens often or the episodes don't resolve quickly, you could fall and even black out.

Does orthostatic hypotension affect the heart? ›

Orthostatic hypotension is a manifestation of abnormal BP regulation due to various conditions, not a specific disorder. Evidence increasingly suggests that disorders of postural hemodynamic control increase risk of cardiovascular disease and all-cause mortality.

What is the most common cause of orthostatic hypertension? ›

What causes orthostatic hypertension?
  • Prolonged bed rest: People who are lying down for extended periods of time may experience OHT.
  • Older age: OHT appears to be more common in older people. ...
  • Medication: Some medications may cause high blood pressure as a side effect.
Aug 23, 2023

Which patient is at highest risk for orthostatic hypotension? ›

Patients with diabetes mellitus are more likely to develop orthostatic hypotension and have an increased risk of mortality, microvascular and macrovascular complications, and cardiovascular events.

What is the 30/20/10 rule for orthostatic hypotension? ›

A decline of ≥20mm Hg in systolic or ≥10 mm Hg in diastolic blood pressure after 3 minutes of standing = orthostatic hypotension. A heart rate increase of at least 30 beats per minute after 3 minutes of standing may suggest hypovolemia, independent of whether the patient meets criteria for orthostatic hypotension.

What diseases cause orthostatic hypertension? ›

Conditions enhancing activation of the sympathetic system and ANS degeneration, such as aging, essential hypertension, diabetes mellitus, and neurological disorders, may be considered as clinical promoters of OHT.2, 4 More specifically, essential hypertension may be bidirectionally linked to OHT.

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